BioNanoDynamics Research team

The BioNanoDynamics research group, part of the Chair of Medical Biotechnology, Faculty of Chemistry, focuses on developing and applying advanced in vitro models to study interactions between nanomaterials (including nanoplastics) and biological systems. Our research integrates microsystems and microfluidic technologies to replicate complex physiological conditions, enabling precise modeling of cellular environments. We utilize cell-on-a-chip and barrier-on-a-chip platforms to investigate nanomaterial-induced effects on cellular function, with particular emphasis on cytotoxicity and biocompatibility. A central field of our work involves developing novel anticancer treatment strategies, including electroporation-based approaches (e.g., electrochemotherapy) and nanoparticle-mediated modalities (e.g., photothermal therapy). Therapeutic efficacy is also assessed using tumor-on-a-chip models. We also design and optimize microfluidic systems for functional sperm selection using tailored microchannel geometries and biologically relevant mechanisms such as chemotaxis.