{"id":8050,"date":"2017-07-18T21:39:10","date_gmt":"2017-07-18T19:39:10","guid":{"rendered":"http:\/\/kbm.ch.pw.edu.pl\/index.php\/sklad-osobowy\/dominik-kolodziejek-2\/"},"modified":"2026-10-20T10:14:42","modified_gmt":"2026-10-20T08:14:42","slug":"olga-koszowska","status":"publish","type":"page","link":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/sklad-osobowy\/olga-koszowska\/","title":{"rendered":"Olga Koszowska"},"content":{"rendered":"\t\t<div class=\"elementor elementor-8050\">\n\t\t\t<div class=\"elementor-inner\">\n\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section data-id=\"f5fc5e8\" class=\"elementor-element elementor-element-f5fc5e8 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div data-id=\"0502667\" class=\"elementor-element elementor-element-0502667 elementor-column elementor-col-100 elementor-top-column\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div data-id=\"55d71f4\" class=\"elementor-element elementor-element-55d71f4 elementor-widget elementor-widget-spacer\" data-element_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-id=\"15e77d1\" class=\"elementor-element elementor-element-15e77d1 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div data-id=\"e4ff8e2\" class=\"elementor-element elementor-element-e4ff8e2 elementor-column elementor-col-50 elementor-top-column\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div data-id=\"b26859c\" class=\"elementor-element elementor-element-b26859c elementor-widget elementor-widget-image\" data-element_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-image\">\n\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/kbm.ch.pw.edu.pl\/wp-content\/uploads\/2026\/10\/IMG_1755-768x1024.jpeg\" class=\"attachment-medium_large size-medium_large\" alt=\"\" srcset=\"https:\/\/kbm.ch.pw.edu.pl\/wp-content\/uploads\/2026\/10\/IMG_1755-768x1024.jpeg 768w, https:\/\/kbm.ch.pw.edu.pl\/wp-content\/uploads\/2026\/10\/IMG_1755-225x300.jpeg 225w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div data-id=\"2574777\" class=\"elementor-element elementor-element-2574777 elementor-column elementor-col-50 elementor-top-column\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div data-id=\"2c27fb3\" class=\"elementor-element elementor-element-2c27fb3 elementor-widget elementor-widget-heading\" data-element_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Olga Koszowska<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-id=\"340c5fb\" class=\"elementor-element elementor-element-340c5fb elementor-widget elementor-widget-text-editor\" data-element_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-text-editor elementor-clearfix\"><p><span style=\"color: #0d2454;\">Przedmiotem bada\u0144 realizowanych w ramach rozprawy doktorskiej jest saporyna &#8211; bia\u0142ko inaktywuj\u0105ce rybosomy typu I (RIP), charakteryzuj\u0105ce si\u0119 du\u017cym potencja\u0142em aplikacyjnym w nowoczesnych terapiach przeciwnowotworowych jako toksyna terapeutyczna. Kluczowym zagadnieniem jest gwa\u0142towny wzrost cytotoksyczno\u015bci saporyny w warunkach synergii z saponinami &#8211; glikozydami pochodzenia ro\u015blinnego. Poniewa\u017c molekularne pod\u0142o\u017ce tego wsp\u00f3\u0142dzia\u0142ania nie zosta\u0142o dot\u0105d w pe\u0142ni wyja\u015bnione, stanowi to istotne ograniczenie w szerszym wykorzystaniu klinicznym tych substancji. G\u0142\u00f3wnym celem prowadzonych bada\u0144 jest szczeg\u00f3\u0142owe poznanie mechanizmu ucieczki endosomalnej oraz weryfikacja kluczowych hipotez naukowych dotycz\u0105cych tego procesu, co przybli\u017cy nauk\u0119 do opracowania skuteczniejszych strategii leczenia celowanego.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div data-id=\"c346410\" class=\"elementor-element elementor-element-c346410 elementor-align-center elementor-widget elementor-widget-button\" data-element_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t<a href=\"m&#x61;&#x69;l&#x74;&#x6f;:&#x6f;&#x6c;g&#x61;&#x2e;k&#x6f;&#x73;z&#x6f;&#x77;s&#x6b;&#x61;&#46;&#x64;&#x6f;k&#x74;&#x40;p&#x77;&#x2e;e&#x64;&#x75;&#46;&#112;&#x6c;\" class=\"elementor-button-link elementor-button elementor-size-sm\" role=\"button\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t<span class=\"elementor-button-text\">E-mail: &#x6f;&#x6c;&#103;&#97;&#46;k&#x6f;&#x73;&#x7a;&#111;wsk&#x61;&#x2e;&#x64;&#111;kt&#x40;&#x70;&#x77;&#46;&#101;du&#x2e;&#x70;&#x6c;<\/span>\n\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-id=\"cdced19\" class=\"elementor-element elementor-element-cdced19 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div data-id=\"a0a816a\" class=\"elementor-element elementor-element-a0a816a elementor-column elementor-col-100 elementor-top-column\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-id=\"87fe297\" class=\"elementor-element elementor-element-87fe297 elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div data-id=\"bbe79f6\" class=\"elementor-element elementor-element-bbe79f6 elementor-column elementor-col-100 elementor-top-column\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div data-id=\"f4ac444\" class=\"elementor-element elementor-element-f4ac444 elementor-widget elementor-widget-spacer\" data-element_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-id=\"d59264e\" class=\"elementor-element elementor-element-d59264e elementor-section-boxed elementor-section-height-default elementor-section-height-default elementor-section elementor-top-section\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t<div class=\"elementor-row\">\n\t\t\t\t<div data-id=\"5a6d271\" class=\"elementor-element elementor-element-5a6d271 elementor-column elementor-col-100 elementor-top-column\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-column-wrap elementor-element-populated\">\n\t\t\t\t\t<div class=\"elementor-widget-wrap\">\n\t\t\t\t<div data-id=\"0233305\" class=\"elementor-element elementor-element-0233305 elementor-widget elementor-widget-divider\" data-element_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\"><\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Olga Koszowska Przedmiotem bada\u0144 realizowanych w ramach rozprawy doktorskiej jest saporyna &#8211; bia\u0142ko inaktywuj\u0105ce rybosomy typu I (RIP), charakteryzuj\u0105ce si\u0119 du\u017cym potencja\u0142em aplikacyjnym w nowoczesnych terapiach przeciwnowotworowych jako toksyna terapeutyczna. Kluczowym zagadnieniem jest gwa\u0142towny wzrost cytotoksyczno\u015bci saporyny w warunkach synergii z saponinami &#8211; glikozydami pochodzenia [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":4170,"parent":3982,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-8050","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/8050","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/comments?post=8050"}],"version-history":[{"count":2,"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/8050\/revisions"}],"predecessor-version":[{"id":8056,"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/8050\/revisions\/8056"}],"up":[{"embeddable":true,"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/pages\/3982"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/media\/4170"}],"wp:attachment":[{"href":"https:\/\/kbm.ch.pw.edu.pl\/index.php\/wp-json\/wp\/v2\/media?parent=8050"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}