A key aspect of my research is the development of advanced Organ-on-Chip and Multi-Organ-on-Chip microfluidic platforms, enabling faithful recreation of dynamic tissue microenvironments and the study of inter-organ interactions in highly predictive models. Currently, my research focuses on the development and application of advanced in vitro models of biological barriers, such as the blood–brain barrier, the gut–blood barrier, and the endothelial barrier, to investigate intercellular interactions under both physiological and pathological conditions. The work is centered on analyzing the function of these barriers in complex diseases, including depression, inflammatory bowel diseases, and cancer, with particular emphasis on metastatic processes.