The aim of the research is to create an in vitro tumor model and use it to evaluate the effectiveness of cancer therapy using graphene derivatives. The project involves the creation of a tumor model that will be better than standard cell culture methods, imitating the in vivo environment of the tumor. For this purpose, microfluidic Lab-on-a-Chip systems as well as the spatial spheroids co-culture were used. In addition, the project evaluates the suitability of graphene materials in previously known anticancer therapies, mainly in photodynamic therapy (PDT).